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Updated: Feb 20, 2026

A Nonviral Approach to Generate Transient Chimeric Antigen Receptor T Cells Using mRNA for Cancer Immunotherapy
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个性化mRNA疫苗在辅助TNBC中引起了持久的T细胞免疫力

U Sahin1,2,3, M Schmidt4, E Derhovanessian5

  • 1BioNTech Group, Mainz, Germany. ugur.sahin@biontech.de.

Nature
|February 18, 2026
PubMed
概括

个性化mRNA疫苗在三阴性乳腺癌 (TNBC) 中表现有前途. 这项研究发现,新抗原疫苗产生了持久的T细胞反应,大多数患者在长达6年的时间内没有复发.

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