低收入和中等收入国家的抗生素使用模式:系统性审查分析分析
Anant Nepal1, Nilam Bhandari2, Ranjeeta Subedi3
1Nepal Karuna Sewa Samaj, Palpa, Lumbini, Nepal.
概括
抗生素耐药性是一种全球性威胁. 这项审查发现高抗生素处方率,以及低收入和中等收入国家"观察"抗生素的使用情况,需要管理计划.
科学领域:
- 全球健康 全球健康
- 传染性疾病 传染性疾病
- 药理学 药理学是指药理学的学科.
背景情况:
- 抗生素耐药性是一个重大的全球健康挑战,由不适当的抗生素使用驱动.
- 合理使用抗生素对于有效治疗感染和减轻耐药性至关重要.
- 低收入和中等收入国家在抗生素处方模式方面面临着独特的挑战.
研究的目的:
- 系统地审查低收入和中等收入国家的抗生素使用模式.
- 评估抗生素处方与世界卫生组织 (WHO) 的标准相对应.
- 为促进合理使用抗生素和减少耐药性的干预措施提供信息.
主要方法:
- 按照PRISMA指南进行系统审查.
- 在Scopus,Embase和Medline数据库中进行了搜索 (2010年1月至2025年11月).
- 包括来自11个国家的20项横截面研究,使用Kmet批判性评估清单进行评估.
主要成果:
- 平均"抗生素处方的百分比"为51.4% (52.7%是私营部门,49.3%是公共部门).
- 在一些研究中",Watch"抗生素的高使用率 (47.4%-74.0%) 超过了世卫组织的建议.
- 阿莫西西林是最常见的;然而",Watch"抗生素也被广泛使用.
结论:
- 抗生素处方率和"观察"抗生素的使用往往超过了世卫组织在审查的设置建议.
- 实施有效的抗生素管理计划至关重要.
- 需要采取干预措施,以促进合理使用抗生素,并打击这些地区的抗药性.
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