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Updated: Jul 2, 2026

Generalized Psychophysiological Interaction PPI Analysis of Memory Related Connectivity in Individuals at Genetic Risk for Alzheimer's Disease
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Generalized Psychophysiological Interaction PPI Analysis of Memory Related Connectivity in Individuals at Genetic Risk for Alzheimer's Disease

Published on: November 14, 2017

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对ABI3 p.Ser209Phe变体的遗传验证及其对无症状老年人早期脑病理的影响

Mikko Koivumäki1,2, Henna Martiskainen3, Mari Takalo3

  • 1Turku PET Centre, University of Turku, Turku, Finland. mikkkoi@utu.fi.

Alzheimer's research & therapy
|February 19, 2026
PubMed
概括

ABI3S209F基因变异增加了阿尔茨海默病的风险,并导致早期发病. 它的效果在与APOE ε4变体结合时显得更加明显,影响粉样蛋白β沉积.

关键词:
在APOE ε4中.在 ABI3S209F 中使用.阿尔茨海默氏症是阿尔茨海默氏症的一种疾病.芬兰人 芬兰人微质细胞中的微质细胞在PET成像中使用PET成像.乙-粉样蛋白-β-粉样蛋白

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In Vivo Functional Study of Disease-associated Rare Human Variants Using Drosophila06:41

In Vivo Functional Study of Disease-associated Rare Human Variants Using Drosophila

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