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Updated: Feb 20, 2026

Anionic Polymerization of an Amphiphilic Copolymer for Preparation of Block Copolymer Micelles Stabilized by π-π Stacking Interactions
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使用PBPK模拟长效注射剂的目标生物预测性溶解档案 - 从关键生物可用性属性从哪里开始?

Hannah Cleary1,2, Nikoletta Fotaki3, Tim Persoons2,4

  • 1EPSRC-Research Ireland Centre for Doctoral Training in Transformative Pharmaceutical Technologies, School of Pharmacy and Pharmaceutical Sciences, Trinity College Dublin, Dublin, Ireland.

CPT: pharmacometrics & systems pharmacology
|February 19, 2026
PubMed
概括

开发长效注射剂 (LAI) 的生物预测溶解试验需要了解体内参数. 基于生理学上的药理动力学 (PBPK) 模型模拟了较慢的LAI溶解,指导了体外试验开发.

关键词:
生物可用性属性是指生物可用性属性.生物预测性性能测试是指生物预测性性能测试.溶解测试 溶解测试 溶解测试长期作用的注射剂.药物动力学建模 药物动力学建模

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