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Updated: Feb 20, 2026

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抗原编码的循环单链DNA用于癌症疫苗

Rui Liu1, Rui Ye2, Guang Hu3

  • 1Faculty of Health Sciences, University of Macau; Taipa, Macau, China; Hangzhou Institute of Medicine, Chinese Academy of Sciences; Hangzhou, Zhejiang, 310022 China.

Molecular therapy : the journal of the American Society of Gene Therapy
|February 19, 2026
PubMed
概括

循环单链DNA (Css DNA) 为癌症疫苗提供了一个稳定,低免疫性平台,性能优于mRNA. 这种新型载体实现了长时间的抗原表达,抑制瘤生长和复发,改善了癌症免疫疗法.

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