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IL-21可以选择性地增加抗原激活MAIT细胞的细胞毒性潜力

Laura E Wedlock1, Rajesh Lamichhane1, Meg C Webley1

  • 1Department of Microbiology and Immunology, University of Otago, Dunedin, New Zealand.

European journal of immunology
|February 19, 2026
PubMed
概括

干白素-21 (IL-21) 增强了粘膜关联不变T细胞 (MAIT) 的细胞毒性潜力. 这种细胞因子增强了MAIT细胞的B粒酶和穿孔素的表达,提高了它们消除受感染细胞的能力.

关键词:
一个IL-21,一个IL-21.在TCR激活时,TCR会被激活.协同刺激是一种共同刺激.细胞毒性 细胞毒性粘膜相关的不变T细胞

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