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Updated: Feb 20, 2026

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该Znf711-Phf8复合体作为转录性静体,对中性粒细胞发育至关重要

Shuiyi Tan1, Huihui Qian2, Haihong Wang2

  • 1Shanghai Institute of Hematology, State Key Laboratory of Medical Genomics, National Research Center for Translational Medicine at Shanghai, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200025, China; CNRS IRP (International research Project), Cancer, Aging and Hematology, Sino-French Research Center for Life Sciences and Genomics, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200025, China; Department of Hematology, Huashan Hospital, Fudan University, Shanghai 200040.

Haematologica
|February 19, 2026
PubMed
概括

以前认为可以激活转录的Znf711-Phf8复合体实际上抑制了中性粒细胞的发育. 这一发现揭示了一种控制中性粒细胞成熟的新机制.

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