运动方式和强度对心血管疾病患者内皮功能的影响:系统性审查和网络元分析
Laura Fuertes-Kenneally1,2,3, Sabina Baladzhaeva1,2, Agustín Manresa-Rocamora1,2
1Institute for Health and Biomedical Research of Alicante (ISABIAL), 03010 Alicante, Spain.
European journal of preventive cardiology
|February 19, 2026
概括
高强度间歇有氧运动 (HIIE) 在心血管疾病患者中显著改善内皮功能. HIIE是血管适应最有效的运动方式,其表现优于其他运动类型.
科学领域:
- 心血管疾病研究研究
- 运动生理学 运动生理学
- 内皮细胞功能 内皮细胞功能
背景情况:
- 内皮功能障碍是心血管疾病 (CVD) 的关键指标.
- 众所周知,运动可以改善内皮功能,但最佳的模式和强度尚未明确定义.
- 流媒扩张 (FMD) 是内皮功能的主要指标.
研究的目的:
- 评估有氧运动 (AE),抵抗运动 (RE) 和联合运动 (CE) 对内皮功能 (FMD) 的影响.
- 为了比较不同强度和运动方式在心血管疾病患者的疗效.
主要方法:
- 随机和非随机试验的系统审查和频率网络元分析.
- 包括患有冠状动脉疾病或慢性心力衰竭的成年人.
- 干预包括常规护理 (UC),中度强度AE (MAE),高强度间隔AE (HIIE),中度强度RE (MRE),高强度RE (HRE),中度强度CE (MCE) 和高强度CE (HCE).
主要成果:
- 与UC相比,MAE,HIIE,MCE和HCE显著改善了手臂口炎.
- 与MAE相比,HIIE在口病中表现出更好的改善.
- 敏感性分析确定HIIE是改善内皮功能最有效的干预措施.
结论:
- 运动干预措施,特别是HIIE,在患有心血管疾病的患者中显著增强内皮功能.
- 在心脏康复中,HIIE是改善血管适应性的最有证据和最有效的方法.
- 需要进一步的随机试验来确认高强度联合炼方案 (HCE) 的有效性.
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