功能性感官症状和症状:一项对102名患者的病例控制研究
Glenn Nielsen1, Rory Higgins1,2, Jon Stone3
1Neuroscience and Cell Biology Research Institute, City St George's, University of London, London SW17 0RE, UK.
Brain communications
|February 19, 2026
概括
在功能神经障碍 (FND) 中,感官症状非常普遍,影响96%的患者,并且经常持续长期. 这些症状具有临床意义,与心理困扰有关,需要在FND护理中进行例行评估.
科学领域:
- 神经学 神经学
- 精神病学是一个精神病学.
- 神经科学是一个神经科学.
背景情况:
- 患者经常报告感官症状,但其患病率,特征和在功能神经障碍 (FND) 中的临床相关性仍然不清楚.
- 了解这些症状对于准确的诊断和在FND中有效的治疗计划至关重要.
研究的目的:
- 估计运动FND患者感官症状的频率和探讨其特征.
- 将这些感觉特征与最近中风患者的感觉特征进行比较.
- 调查功能性感官症状潜在的潜在机制.
主要方法:
- 一项前性观察队列研究,涉及102名运动FND患者和75名近期中风患者.
- 使用结构化临床采访,身体图,验证问卷,临床评估和定量感官测试.
- 动力FND参与者的12个月后跟踪,使用专题分析,描述性统计和回归模型分析数据.
主要成果:
- 与最近的中风 (67%) 相比,运动FND (96%) 的感觉症状非常普遍,其中包括肢体缺失和完全感觉丧失的独特描述.
- 运动FND患者报告疼痛更频繁 (88%),并经历了更高的分离率,身体感知障碍和感官过敏.
- 感官症状严重,与残疾和抑郁症相关,在12个月后表现出有限的改善,定量感官测试几乎没有诊断价值.
结论:
- 运动性FND的感觉症状非常普遍,持久,多样化,临床意义重大,通常与更广泛的疾病负担和心理痛苦同时发生.
- 在FND中,建议对感官症状进行例行评估,以诊断和治疗计划.
- 未来的研究应该集中在针对性干预的感官症状在多学科康复框架内为FND.
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