通过上肢DVT复杂的dantrolene成功治疗恶性高温症:一个病例报告
Mostafa Nagy1,2,3,4, Syed Nasir Mustafa1,2,3, Rayan Muawad1,2,3
1Department of Anesthesia, King Abdullah Specialized Children Hospital, Riyadh, Saudi Arabia.
Saudi journal of anaesthesia
|February 19, 2026
概括
恶性高温症 (MH) 是一种罕见但危险的麻醉反应,发生在接受鼻手术的患者身上. 用dantrolene迅速治疗导致完全康复,尽管在接受治疗的肢体中发生了深静脉血栓塞 (DVT).
科学领域:
- 麻醉学 麻醉学
- 药理学 药理学是指药理学的学科.
- 临界护理医学 临界护理医学
背景情况:
- 恶性高温症 (MH) 是一种罕见的,危及生命的全身麻醉的高代谢并发症.
- 由挥发性麻醉剂和顺胆引发的MH在手术室中构成了重大挑战.
- 这一案例突显了在没有病史或家庭倾向的患者中突然出现的MH.
研究的目的:
- 在功能性内镜外科手术 (FESS) 期间报告恶性高温症 (MH) 病例.
- 强调早期识别和迅速管理MH的重要性.
- 讨论 MH 治疗后可能出现的并发症.
主要方法:
- 一名40岁的男性患者在FESS的麻醉诱导后45分钟就出现了MH的症状.
- 诊断出MH的临床症状,并立即给出了dantrolene.
- 启动了支持性护理措施,包括对超能代谢的积极管理.
主要成果:
- 患者从MH的急性代谢危机中完全康复.
- 尽管成功管理了MH,但患者在丹特罗被施用的肢体上发展了上肢深静脉血栓症 (DVT).
- 在患者身上没有相关的家族病史或先前麻醉并发症.
结论:
- 早期诊断和丹特罗的快速管理对于成功的MH管理至关重要.
- 麻醉科医生必须对MH保持警,即使在没有已知的危险因素的患者中也是如此.
- 深静脉血栓形成 (DVT) 在MH病例中可能是dantrolene后的潜在并发症.
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