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Updated: Feb 20, 2026

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Prdm16放大了痕信号,并抑制了静脉谱系的规范,以防止血管发育期间的动脉静脉形

Jore Van Wauwe1, Pavithra Janarthanan2,3, Sander Craps1

  • 1Department of Cardiovascular Sciences, Center for Molecular and Vascular Biology, KU Leuven, Belgium (J.V.W., S.C., P.V., H.K., M.D., A.L.).

Arteriosclerosis, thrombosis, and vascular biology
|February 19, 2026
PubMed
概括

转录因子Prdm16 (正调节域含蛋白 16) 通过与Notch信号交互来促进动脉内皮细胞的身份. 这种相互作用对血管发育至关重要,并可能为动脉静脉形形提供治疗点.

关键词:
动脉静脉形形的发生它们是内皮细胞.鼠标 鼠标 鼠标 鼠标转录因子是一种转录因子.斑马鱼是一种斑马鱼.

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