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巴西儿科重症监护室的实践和结果,在执行了关键支气管炎协议后
Patricia Silva Vasconcellos de Lara1, Andrew G Miller2,3, Leandro Candido de Souza4
1Dr. de Lara is affiliated with Department of Pediatrics, Hospital da Luz, São Paulo, SP, Brazil.
在巴西的PICU中,关键性支气管炎的管理显示了低的输管率,即使不完全遵守协议. 修改后的Wood-Downes评分 (mWDS) 有效地预测了婴儿机械通风的需要.
科学领域:
- 儿科 儿科 儿科
- 密集护理医学 密集护理医学
- 呼吸系统医学 呼吸系统医学
背景情况:
- 严重的支气管炎是儿童重症监护室 (PICU) 入院的常见原因.
- 关键支气管炎的管理策略有很大的不同,南美PICU的数据有限.
- 这项研究解决了在巴西PICU背景下对关键支气管炎的表征的需求.
研究的目的:
- 在巴西的PICU中描述关键支气管炎轨迹.
- 评估遵守临床协议,减轻辅助药理治疗的重视.
- 评估修改后的Wood-Downes分数 (mWDS) 以指导呼吸支和预测机械通风需求.
主要方法:
- 24个月以下患有严重支气管炎的婴儿的回顾性队列研究 (2021年3月至2023年4月).
- 协议不鼓励吸入β-激动剂,全身皮质类固醇和吸入高血压盐水.
- 由mWDS指导的呼吸辅助:常规氧气 (≤3),HFNC/NIV (4-7),机械通风 (>7).
主要成果:
- 研究了299名婴儿;69%患有RSV感染.
- 输管率低 (3%); 61%的人接受常规氧气,22%的HFNC,14%的NIV.
- 完整的协议遵守率为43%;入院时的mWDS预测了输管 (AUC0.77),得分<4表明不需要输管.
结论:
- 巴西PICU队列显示,尽管遵守了不理想的协议,但临界支气管炎的输管率很低.
- 在PICU入院时的mWDS得分是对机械通风需求的可靠预测指标.
- 在入院时mWDS得分低于4的婴儿是低风险的婴儿,不需要输管.
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