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相关概念视频

Mitral Regurgitation I: Introduction01:20

Mitral Regurgitation I: Introduction

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Mitral regurgitation is characterized by the backward circulation of blood from the left ventricle to the left atrium during systole, a phase of the cardiac cycle when the heart contracts and pumps blood out of the chambers. This abnormal flow occurs primarily due to the dysfunction of the mitral valve or its supporting structures, which include the mitral leaflets, chordae tendineae, annulus, and papillary muscles.Etiology and Mechanisms:Primary Mitral Regurgitation: This type arises from...
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Mitral Stenosis I: Introduction01:22

Mitral Stenosis I: Introduction

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Mitral Valve Stenosis (MVS) is a heart condition where the mitral valve narrows, impeding blood circulation from the left atrium to the left ventricle. The etiology and pathophysiology of this condition are multifaceted, leading to a cascade of cardiovascular complications.Causes of Mitral Valve StenosisRheumatic Heart Disease: It is the main cause of mitral valve stenosis, particularly in developing nations. This condition arises from rheumatic fever, an inflammatory illness resulting from...
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Aortic Regurgitation II: Clinical Features and Diagnostic Tests01:22

Aortic Regurgitation II: Clinical Features and Diagnostic Tests

626
Aortic valve regurgitation (AR) occurs when the aortic valve fails to close properly, allowing blood to flow backward from the aorta into the left ventricle. This backflow can result in two distinct clinical presentations: acute and chronic AR, each characterized by its own set of symptoms and physical findings.Acute Aortic RegurgitationAcute AR presents with a sudden onset of severe symptoms. Patients typically experience profound dyspnea (shortness of breath), chest pain, and signs of left...
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Heart Failure II: Pathophysiology01:29

Heart Failure II: Pathophysiology

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Systolic Heart Failure and Compensatory MechanismsSystolic heart failure (also termed HFrEF, Heart Failure with Reduced Ejection Fraction) is the most prevalent type of heart filure. It results in a decreased volume of blood being pumped from the ventricle. The aortic arch and carotid sinuses have baroreceptors that detect reduced blood pressure, triggering the sympathetic nervous system (SNS) to release epinephrine and norepinephrine. Initially, this response aims to boost heart rate and...
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Cardiomyopathy III: Hypertrophic Cardiomyopathy01:29

Cardiomyopathy III: Hypertrophic Cardiomyopathy

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Hypertrophic cardiomyopathy, or HCM, is an autosomal dominant genetic disorder characterized by asymmetric left ventricular hypertrophy without ventricular dilation. It is more common in men and is typically diagnosed in young, athletic adults.EtiologyHCM is primarily genetic and is caused by mutations in genes encoding sarcomeric proteins. Researchers have identified over 1400 mutations across at least 11 different genes. Among these, the most frequently occurring mutations are found in the...
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Imbalances in Cardiac Output01:26

Imbalances in Cardiac Output

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The heart's primary function is to pump blood throughout the body, maintaining a balance between blood sent out (cardiac output) and blood returning (venous return). If this balance is disrupted, it can result in congestive heart failure (CHF), a severe condition where the heart becomes an inefficient pump, leading to inadequate blood circulation.
CHF can occur due to the failure of either side of the heart. Left-side failure leads to pulmonary congestion—the right side continues to send...
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Estimating Bilateral Atrial Function by Cardiovascular Magnetic Resonance Feature Tracking in Patients with Paroxysmal Atrial Fibrillation
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在左心室功能障碍中,左心室纵向功能与左心房应变之间的关联

Björn Östenson1, Elsa Bergström1, Katarina Steding-Ehrenborg1

  • 1Clinical Physiology, Department of Clinical Sciences Lund, Lund University, Skåne University Hospital, Lund, Sweden.

ESC heart failure
|February 19, 2026
PubMed
概括
此摘要是机器生成的。

左心室 (LA) 储应变受左心室 (LV) 纵向功能在LV功能障碍患者显著影响. 减少LA菌株可能反映了潜在的LV问题,而不是独立的心脏标志物.

关键词:
在CMR中,CMR是CMR.心房功能的心房功能.心心室合器的合方式全球纵向菌株全球纵向菌株腹腔功能 腹腔功能

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科学领域:

  • 心脏病学 心脏病学
  • 心脏成像 - - 心脏成像
  • 生理学 生理学 生理学

背景情况:

  • 左心室 (LV) 纵向功能是LV功能障碍的关键预后指标.
  • 左心房 (LA) 储和导管应变是新兴的预后标志物.
  • 心房和心室之间的合 (LA-LV合) 对于心脏功能至关重要.

研究的目的:

  • 使用心脏磁共振 (CMR) 特征追踪量化LV纵向功能和LA菌株之间的关联.
  • 为了调查LA菌株是否由LV纵向功能在LV功能障碍中确定.

主要方法:

  • 对342名LV功能障碍患者和19名健康对照患者 (HC) 的回顾性分析.
  • 使用CMR特征追踪分析LV全球纵向应变 (LV-GLS),LV心房平面位移 (AVPD) 和LA全球纵向应变 (LA-GLS).

主要成果:

  • 与HC相比,LV功能障碍组的LA-GLS显著较低 (12±8%与19±7相比,p<0.001).
  • 在LA-GLS的减少反映了LV-GLS (-10±5%与19±3,p<0.001) 和LV-AVPD (9±3毫米与15±2毫米,p<0.001) 的减少.
  • 在LV-GLS和LA-GLS (r2=0.40) 和LV-AVPD和LA-GLS (r2=0.39) 之间发现了强烈的相关性.

结论:

  • 在患有 LV 功能障碍的患者中,LA 储功能 (LA-GLS) 在很大程度上取决于 LV 纵向功能.
  • 在某些患者群体中,LA功能可能不能作为整体心脏功能的独立标志物.
  • 减少LA功能可能是潜在的LV功能障碍的结果.