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Updated: Feb 21, 2026

Quantitation and Analysis of the Formation of HO-Endonuclease Stimulated Chromosomal Translocations by Single-Strand Annealing in Saccharomyces cerevisiae
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乳酸脱酶缺乏的癌细胞对Ym155诱导的DNA损伤的敏感性增加了

Qianjin Guo1, Sooyeon Lee1, Neali Armstrong1

  • 1Department of Medicine, Division of Endocrinology, Stanford University, Stanford, CA, USA.

Endocrine-related cancer
|February 19, 2026
PubMed
概括

与SDHB缺乏症相关的遗传性色细胞瘤和偏角细胞瘤 (hPPGL) 综合征显示出转移风险增加. 研究人员发现,Ym155化疗通过诱导DNA损伤和ROS生成,优先针对SDHB缺乏癌症.

关键词:
造成的DNA损伤是DNA损伤.线粒体的氧化还原失衡是线粒体的不平衡.红斑细胞瘤和偏角细胞瘤 (PPGL)Succinate 脱水酶 的作用.Ym155 是一个155的字母.细胞癌瘤是细胞癌.合成杀伤性 合成杀伤性

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