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在40岁左右的美国人中,多种疾病模式和肥胖症
Xinyu Zhu1, Rebecca Jones-Antwi2, Solveig A Cunningham3,4
1Nutrition and Health Sciences Program, Laney Graduate School, Emory University, Atlanta, GA, USA.
American journal of health promotion : AJHP
|February 19, 2026
概括
进入40多岁的成年人的多病态模式包括关节炎-精神健康和高血压-糖尿病集群. 肥胖显著增加了这两种普遍的多重疾病模式的风险.
科学领域:
- 公共卫生 公共卫生
- 流行病学 流行病学
- 慢性疾病管理 慢性疾病管理
背景情况:
- 多病性,即两个或两个以上的慢性疾病同时发生,是越来越严重的公共卫生问题,特别是随着个体的老龄化.
- 了解多病症的具体模式对于制定有针对性的干预措施和医疗保健策略至关重要.
- 进入40多岁的成年人代表了一个关键的过渡期,在这个时期可能出现慢性疾病的早期迹象.
研究的目的:
- 为了在40岁左右的美国成年人中识别明显的多病态模式.
- 调查肥胖与这些已识别的多病症模式之间的关联.
主要方法:
- 1979年全国青年纵向研究 (n=8104) 数据的横截面分析.
- 隐性类分析被用来识别基于7种慢性疾病的自我报告诊断的多病症模式.
- 多项逻辑回归研究了肥胖 (BMI ≥30 kg/m2) 与疾病集群之间的关联.
主要成果:
- 在41岁的平均年龄,10.8%的成年人患有多病症,26.3%患有肥胖症.
- 确定了三种多病态模式:"健康"组 (≤1状况),"关节炎-精神健康状况主导"集群 (5.6%),以及"高血压-糖尿病主导"集群 (2.4%).
- 肥胖与两种多病症群体都有很强的关联,对"高血压-糖尿病"群体 (OR=5.2) 和"关节炎-精神健康"群体 (OR=1.7) 的几率明显更高.
结论:
- 在40多岁的美国成年人中,多种疾病集中在关节炎 - 精神健康和高血压 - 糖尿病条件周围.
- 肥胖是一个显著的风险因素,不成比例地影响这些普遍的多病症集群中的个人.
- 这些发现强调了肥胖管理在预防和解决中年成人多病症方面的重要性.
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