双极性障碍的认知投诉:与估计的疾病相关目标认知衰退,功能和生活质量的关系
Johanna Mariegaard Schandorff1,2, Jeff Zarp1,3, Anne Juul Bjertrup1
1Neurocognition and Emotion Across Disorders of the Brain (NEAD) Centre, Psychiatric Centre Copenhagen, Mental Health Services, Capital Region of Denmark, Frederiksberg, Denmark.
Bipolar disorders
|February 19, 2026
概括
双相情感障碍 (BD) 的认知投诉可能表明以前的认知功能下降,即使测试结果正常. 解决这些主观问题是改善功能和生活质量的关键.
科学领域:
- 神经科学是一个神经科学.
- 精神病学是一个精神病学.
- 认知心理学 认知心理学
背景情况:
- 双极性障碍 (BD) 通常涉及认知问题,但它们的起源 (偏见与衰退) 和对功能的影响仍然存在争议.
- 客观认知测试可能并不总是捕捉到BD患者认知障碍的主观经验.
- 了解主观和客观认知措施之间的关系对于患者的福祉至关重要.
研究的目的:
- 调查双相情感障碍患者认知投诉和认知表现之间的联系.
- 确定主观认知困难是否预测功能结果和生活质量.
- 区分认知衰退与病前水平之间的差异以及潜在的负面偏见.
主要方法:
- 在七项研究中分析了498名BD患者和320名健康对照者的数据.
- 计算差异分数:智商-客观认知和主观-客观认知.
- 使用多重回归模型来评估与认知投诉,功能和生活质量相关的关联.
主要成果:
- 主观认知问题与预先患病智商相比,估计的"功能丧失"更大.
- 与客观发现相比,主观认知困难的程度更高与功能和生活质量下降有关.
- 客观认知表现也显示出与功能和生活质量下降的类似关联.
结论:
- 在BD的认知投诉可能反映了从病前认知功能下降,不管当前的客观表现.
- 主观和客观认知评估之间的差异是功能结果和生活质量的重要预测因素.
- 认知管理策略应优先考虑报告认知投诉的患者,无论客观测试结果如何.
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