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Updated: Feb 21, 2026

Methods for the Discovery of Novel Compounds Modulating a Gamma-Aminobutyric Acid Receptor Type A Neurotransmission
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Methods for the Discovery of Novel Compounds Modulating a Gamma-Aminobutyric Acid Receptor Type A Neurotransmission

Published on: August 16, 2018

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针对反应性中间体的合规灵活性,以提高GABA氨基转移酶失活剂的选择性

Koon Mook Kang1,2, Abigail L Vargas3, Luana Assis Ferreira4

  • 1Department of Chemistry, Northwestern University, Evanston, Illinois 60208, United States.

Journal of the American Chemical Society
|February 19, 2026
PubMed
概括

针对γ-aminobutyric acid aminotransferase (GABA-AT) 的基于机制的非激活剂 (MBIs) 面临选择性挑战. 这项研究揭示了CPP-11515的存在.

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