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Updated: May 11, 2026

Application of CRISPR Interference (CRISPRi) for Gene Silencing in Pathogenic Species of Leptospira
14:49

Application of CRISPR Interference (CRISPRi) for Gene Silencing in Pathogenic Species of Leptospira

Published on: August 14, 2021

莱普托斯皮拉的CdaA蛋白是一种功能性滴氨酸环酸酶

Edward J A Schuler1, Dhara T Patel1, Aidan D Moylan1

  • 1Department of Microbiology and Immunology, Virginia Commonwealth University Medical Center, Richmond, Virginia, USA.

Infection and immunity
|February 19, 2026
PubMed
概括

研究人员在Leptospira interrogans中发现了一种功能性二甲酸环酶 (DAC) 酶CdaA. 这种酶合成循环二氨酸单酸盐 (c-di-AMP),对于细菌的适应和病变产生至关重要.

关键词:
在CdaAA中使用.LIC1084444 这是一个很好的机会.莱普托斯皮拉 (Leptospira) 是一个类动物.c-di-AMP 的时间.迪亚迪尼酸环酸.莱普托斯皮罗斯症是什么?透调节是指透调节.

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