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Updated: May 9, 2026

Whole Genome Sequencing of Candida glabrata for Detection of Markers of Antifungal Drug Resistance
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雷扎丁在抗可纳和耐火性角膜炎中:巴西的第一个经验

Wdson Luis Lima Kruschewsky1, Jeanne Aiko de Souza Nakagawa1, Lumena Pereira Machado Siqueira2

  • 1Universidade de São Paulo, Faculdade de Medicina, Hospital das Clínicas, Divisão de Clínica de Moléstias Infecciosas e Parasitárias, São Paulo, São Paulo, Brazil.

Revista do Instituto de Medicina Tropical de Sao Paulo
|February 19, 2026
PubMed
概括

雷扎丁 (Rezafungin) 提供了一种针对侵袭性候群病的新疗法,在两名巴西患者中表现出成功,这些患者患有难以治疗的真菌感染,对其他抗真菌药物有抗性.

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相关概念视频

Antifungal Agents01:15

Antifungal Agents

Amphotericin B is a broad-spectrum antifungal agent that exploits structural differences between fungal and mammalian cell membranes. Its amphipathic structure—featuring a hydrophobic polyene-lactone ring and a hydrophilic region containing mycosamine and carboxylic acid groups—enables selective binding to ergosterol, a sterol predominantly found in fungal plasma membranes. This selective interaction underlies the drug’s antifungal activity, although weak binding to cholesterol contributes to...