心脏事件诱导的PTSD症状和冠状动脉疾病患者的持续心率
Maia Ten Brink1, Joseph E Schwartz1, Talea Cornelius1
1Center for Behavioral Cardiovascular Health, Department of Medicine, Columbia University Irving Medical Center.
概括
增加的创伤后压力症状 (PSS) 与心脏病患者心率的增加有关. 准PSS可能有助于减少同情性兴奋并改善心脏健康结果.
科学领域:
- 心脏病学 心脏病学
- 精神病学是一个精神病学.
- 心理生理学 心理生理学
背景情况:
- 创伤后压力症状 (PSS) 影响大约13%的冠状动脉疾病患者的心脏事件后.
- 升高的PSS可能会通过交感神经系统活动和心率增加 (HR) 增加复发性心脏事件的风险.
研究的目的:
- 调查PSS之间的关联,使用DSM-5 (PCL-5) 的创伤后应激障碍检查清单进行评估,以及心脏病患者的门诊HR升高.
- 为了确定这种关联是否独立于PSS相关的健康行为而持续存在.
主要方法:
- 招募了116名最近出院的心脏病患者,他们的PSS被分类为升高 (PCL-5 ≥20) 或不升高 (PCL-5 ≤5).
- 参与者接受了24小时的门诊心电图监测和两周的手腕动图.
- 贝塔阻断剂的坚持被电子追踪.
主要成果:
- 连续增加的PSS得分与每增加10点的PSS每分钟高出1.6节拍的HR显著相关 (p = .009).
- 在调整了白天HR变化,人口统计,心脏风险,并发病,体力活动,睡眠时间和β-阻断剂坚持之后,这种关联仍然显著.
结论:
- 研究结果表明,针对心脏病患者的PSS可能有助于减轻慢性同情性兴奋.
- 密集的监测和高分辨率的行为数据支持在这个人群中心理困扰和高HR之间的生理联系.
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