激素治疗诱导的手关节痛在乳腺癌患者的非药理学干预的有效性:一个系统性审查
Nuria Muñoz-Bermúdez1,2, Vanessa Abril-Esteban1, Jorge Hugo Villafañe1
1Universidad Europea de Madrid. Faculty of Medicine, Health and Sports. Madrid, Spain.
Journal of evidence-based integrative medicine
|February 19, 2026
概括
针和结构化炼在乳腺癌幸存者中为芳酶抑制剂诱导的关节痛 (AIA) 提供了显著的缓解. 这些非药理学方法在治疗关节疼痛和改善生活质量方面表现有前途.
科学领域:
- 在瘤学瘤学.
- 类风湿病学 类风湿病学
- 基于证据的医学基于证据的医学.
背景情况:
- 芳酶抑制剂诱导的关节痛 (AIA) 是乳腺癌内分泌治疗的常见副作用.
- AIA可能会对治疗的坚持和患者的生活质量产生负面影响.
- 目前,关于非药物治疗AIA的证据是分散的.
研究的目的:
- 系统地审查最近对AIA的非药物干预的随机对照试验 (RCT).
- 综合各种非药理学策略在管理AIA中的有效性.
主要方法:
- 在PubMed,Scopus和Web of Science (2010-2025) 的系统文献搜索.
- 包括评估非药物干预措施的RCT用于AIA.
- 独立的研究选择,数据提取和质量评估由两名审查员进行.
主要成果:
- 包括八个RCT,评估针,结构化炼,放松和带.
- 针证明了临床上有意义的疼痛减轻 (BPI上的0.9-1.1分).
- 结构化炼 (有氧运动,抵抗运动,皮拉特斯运动) 显示疼痛,功能和生活质量有中等改善.
结论:
- 针和结构化炼是目前对AIA最有效的非药物干预措施.
- 纳入试验的整体方法质量中等.
- 需要进一步进行具有标准化结果的高质量的RCT,包括对职业治疗的探索.
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