成年人急性间歇性炎:突尼斯脏病学中心的一系列病例回顾
Sanda Mrabet1, Nermine Ben Achour1, Raja Boukadida1
1Nephrology Department, Sahloul University Hospital, Street Route Ceinture Sahloul, 4054, Sousse, Tunisia.
La Tunisie medicale
|February 19, 2026
概括
突尼斯的急性间歇性炎 (AIN) 通常是药物诱导的,大多数患者在接受皮质类固醇治疗后恢复功能. 间歇性纤维化可以导致慢性病.
科学领域:
- 腎臟病學 (nephrology) 是一種醫學專業.
- 病理学 病理学 病理学
- 临床医学 临床医学
背景情况:
- 急性间歇性炎 (AIN) 是急性损伤 (AKI) 的重要原因之一.
- AIN的发病率和原因在地理位置上有所不同.
- 了解当地AIN特点对于有效管理至关重要.
研究的目的:
- 研究突尼斯人口中AIN的临床特征,病因,诊断方法,治疗和结果.
- 确定该地区AIN的特定触发因素和风险因素.
- 为了评估长期的结局和进展到慢性病.
主要方法:
- 16年来活检证明的AIN病例的回顾性分析.
- 数据收集包括患者人口统计,临床表现,实验室值,脏活检结果,治疗和随访.
- 统计分析确定的原因,治疗反应和功能恢复.
主要成果:
- 确定了36例AIN病例,平均年龄为50.58岁.
- 疲劳和发烧是常见的症状;平均肌素为691.58μmol/l.
- 药物诱导的原因是最常见的 (46.66%),其次是感染 (16.66%) 和全身性疾病 (11.11%).
- 特殊原因包括Rituximab治疗和寄生虫感染.
- 25%的病例的病因不明.
- 在93.33%的病例中使用皮质类固醇,其中71.42%的功能恢复.
- 间歇性纤维化与慢性病进展有关.
结论:
- AIN是AKI的主要原因,具有慢性化潜力.
- 药物摄入是AIN的主要原因.
- 间歇性纤维化是不良结局和进展为慢性病的关键预测因素.
- 需要进一步的研究来确定未知的病因.
相关概念视频
01:30Urinary Tract Infection III: Diagnostic Studies and Interprofessional Care
434
A healthcare provider can diagnose a urinary tract infection (UTI) through several methods:Medical History and Symptoms: The provider will take a detailed medical history and ask about symptoms such as frequent urination, burning sensation during urination, and lower abdominal pain.Urinalysis: A clean-catch urine sample is collected in a sterile container and tested for the presence of bacteria, white blood cells (leukocytes), nitrites, blood, and protein. The presence of leukocytes and...
434
01:27Acute Pyelonephritis I: Introduction
1.5K
Pyelonephritis is a bacterial infection that primarily affects the renal parenchyma and collecting system, including the renal pelvis, tubules, and interstitial tissue of one or both kidneys. It can be classified as either acute—a sudden, severe infection—or chronic, which refers to long-term or recurrent kidney infections.The primary cause of acute pyelonephritis (APN) is bacterial infection, with Escherichia coli accounting for approximately 70-80% of cases. Other bacteria, such...
1.5K
01:28Acute Pyelonephritis II: Diagnostic Studies and Management
842
Introduction:For diagnosing acute pyelonephritis, a comprehensive patient history is collected to identify symptoms such as dysuria, frequent or urgent urination, flank pain, or costovertebral angle (CVA) tenderness that may suggest a kidney infection.Physical ExaminationDuring the physical examination, CVA tenderness is assessed. This involves gentle percussion over the costovertebral angle, where tenderness often indicates a kidney infection.Diagnostic TestsUrinalysis: Used to identify white...
842
01:24Nephrotic Syndrome I : Introduction
1.2K
Nephrotic Syndrome is a chronic kidney disorder defined by clinical findings such as severe proteinuria, hypoalbuminemia, hyperlipidemia, and edema. These symptoms result from damage to the glomeruli, the kidney’s filtering units, increasing their permeability to proteins.Definition and Meaning:Proteinuria, defined as the loss of more than 3.5 grams of protein per day in adults, is a crucial feature of nephrotic syndrome. This condition is often accompanied by edema, the accumulation of...
1.2K
01:29Acute Kidney Injury II: Pathophysiology
2.3K
Acute kidney injury (AKI) causes are categorized into three primary categories based on the location of the injury: prerenal, intrarenal (or intrinsic), and postrenal causes. This classification guides clinical management and illustrates how different pathways can impair kidney function.Etiology and Pathophysiology of Acute Kidney Injury1. Prerenal causesEtiology: Prerenal Acute Kidney Injury, the most common type, occurs when reduced blood flow to the kidneys decreases filtration capacity...
2.3K
01:30Acute Kidney Injury IV: Diagnostic Studies and Prevention
559
Accurate diagnosis and effective prevention are critical in managing Acute Kidney Injury (AKI), which is linked to high mortality rates ranging from 10% to 80%. Timely recognition of at-risk patients and careful monitoring can significantly reduce the likelihood of kidney damage.Diagnostic Assessments:The diagnostic process starts with a comprehensive medical history to identify prerenal, intrarenal, and postrenal causes.Prerenal causes, such as dehydration, hypotension, or blood loss, should...
559