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相关概念视频

Development of Immunocompetence01:22

Development of Immunocompetence

1.0K
The initiation of cell-mediated immunity can be observed as early as the third month of fetal growth, with active antibody-mediated immunity following approximately one month later.
The initial cells that migrate from the fetal thymus settle within the skin and epithelial tissues lining the mouth, digestive tract, and in females, the uterus and vagina. These cells, including skin-based dendritic cells, serve as antigen-presenting cells, playing a key role in T cell activation.
Subsequent T...
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Transcytosis of IgG01:15

Transcytosis of IgG

4.2K
Transcytosis is the process in which molecules are internalized by endocytosis, transported across the cell, and released through exocytosis from the opposite end of the cell. Molecules such as insulin, immunoglobulins, and certain nutrients are transferred through the recycling endosomes by recycling and transcytosis.
IgG molecules from a mother undergo transcytosis starting around 13 weeks of gestation. The amount of IgG transferred and entering the fetal blood circulation increases with...
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Vaccinations01:51

Vaccinations

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Overview
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Active versus Passive Immunity01:31

Active versus Passive Immunity

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Immunity, along with the ability to limit pathogen growth to prevent significant body tissue damage, can be gained either by (1) actively developing an immune response within the individual after exposure to a pathogen or after getting vaccinated or (2) passively transferring immune components from an immune individual to one who is nonimmune. Both these forms of immunity can be found naturally and in medical practices.
Active Immunity
Active immunity refers to the resistance one develops...
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Immunological Memory01:23

Immunological Memory

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Immunological memory, a pivotal pillar of the adaptive immune system, is responsible for the body's ability to remember and respond more swiftly and effectively to previously encountered pathogens. This remarkable feature is what makes vaccines so effective in preventing diseases.
What is Immunological Memory?
Immunological memory is an integral function of the immune system that allows it to recognize and react more rapidly and effectively to pathogens previously encountered. This feature...
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相关实验视频

Updated: Feb 21, 2026

Intranasal Immunization and Milk Collection in Studies of Maternal Immunization in New Zealand White Rabbits Oryctolagus cuniculus
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孕产妇免疫接种方式

Denise J Jamieson1, Flor M Munoz, Sonja A Rasmussen

  • 1University of Iowa Health Care, Iowa City, Iowa; the Division of Infectious Diseases, Department of Pediatrics, and the Department of Molecular Virology and Microbiology, Baylor College of Medicine, Houston, Texas; and the Department of Genetic Medicine and the Department of Gynecology and Obstetrics, Johns Hopkins University School of Medicine, Baltimore, Maryland.

Obstetrics and gynecology
|February 19, 2026
PubMed
概括
此摘要是机器生成的。

孕产妇免疫安全地保护母亲和婴儿免受传染病. 推的疫苗如Tdap,流感,COVID-19和RSV都能为母亲和孩子提供抗体保护.

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Induction of Maternal Immune Activation in Mice at Mid-gestation Stage with Viral Mimic PolyI:C
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Intranasal Immunization and Milk Collection in Studies of Maternal Immunization in New Zealand White Rabbits Oryctolagus cuniculus
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Induction of Maternal Immune Activation in Mice at Mid-gestation Stage with Viral Mimic PolyI:C
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Generating a Reproducible Model of Mid-Gestational Maternal Immune Activation using PolyI:C to Study Susceptibility and Resilience in Offspring
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科学领域:

  • 产科和妇科 产科和妇科
  • 免疫学 免疫学 免疫学
  • 传染性疾病 传染性疾病

背景情况:

  • 孕产妇免疫接种为孕妇和婴儿提供了对传染病的双重保护.
  • 通过胎盘和母乳传递的抗体为新生儿提供了被动免疫力,这些新生儿太年轻,无法接种疫苗.
  • 无活化疫苗在怀孕期间通常是安全的,而由于理论上的胎儿风险,通常会避免活体减弱疫苗.

研究的目的:

  • 审查目前关于在怀孕期间接种妇女疫苗的建议.
  • 突出孕产妇免疫的好处,以保护母亲和婴儿.
  • 讨论正在进行的关于与怀孕相关的新疫苗的研究,例如B组链球菌 (GBS).

主要方法:

  • 对当前关于母婴疫苗接种的科学文献和临床指导方针的审查.
  • 在怀孕期间分析疫苗的安全性和有效性.
  • 对孕妇群体的推和有条件推疫苗的检查.

主要成果:

  • 在美国,建议在怀孕期间进行常规接种毒素,减少的耳毒素和非细胞性百日咳 (Tdap),流感,COVID-19和RSV疫苗.
  • 孕产妇免疫策略提高抗体度,为婴儿提供直接和间接的保护.
  • 疫苗接种在预防严重的母亲和婴儿疾病方面的好处通常超过潜在的风险.

结论:

  • 孕产妇免疫是改善孕产妇和婴儿健康结果的关键公共卫生战略.
  • 持续研究和开发针对怀孕特异性传染病的疫苗至关重要.
  • 怀孕期间接种疫苗的决定应该平衡疾病风险与接种疫苗的好处,考虑到个体情况.