在哺乳母猪的唾液代谢物组成,pH值和胃之间的关联研究
L C Salazar1, E M Baxter1, A B Lawrence2
1Scotland's Rural College, Veterinary and Animal Sciences, West Mains Road, Edinburgh EH9 3JG Scotland, UK.
Animal : an international journal of animal bioscience
|February 19, 2026
概括
唾液分析显示了检测猪胃的潜力,这是一个常见的问题,引起疼痛. 特定的唾液代谢物,而不是pH值,可能是这种隐藏的福利问题的早期生物标志物.
科学领域:
- 兽医医学 兽医医学 兽医医学
- 动物科学动物科学
- 生物化学 生物化学
背景情况:
- 胃在猪中很普遍,造成疼痛和经济损失.
- 目前用于胃的诊断方法具有侵入性,限制了它们在活体动物中的使用.
- 需要进行非侵入性诊断来了解和管理猪胃.
研究的目的:
- 探索唾液代谢物组成和pH值作为检测活猪胃的非侵入性工具.
- 评估使用唾液分析用于母猪胃诊断的可行性.
主要方法:
- 在安乐死之前,从26头母猪收集了唾液样本.
- 在唾液上进行了全球代谢和通路丰富分析.
- 测量了唾液pH值,并使用评分系统评估了死后胃的完整性.
主要成果:
- 69.2%的母猪表现出胃,有中度至严重的食道病变.
- 唾液pH与胃的完整性没有相关性.
- 代谢分析确定了与食道完整性变化相关的特定唾液代谢物,包括L-histidine和lipoxin A4.
结论:
- 唾液代谢产物显示出潜在的非侵入性生物标志物作为潜在的非侵入性生物标志物用于母猪的胃.
- 在这个人群中,唾液pH值不是胃的可靠指标.
- 胃潰瘍在豬產業中代表了一個重要的,可能"隱藏"的福利問題.
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