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Updated: May 5, 2026

Generation of Immature, Mature and Tolerogenic Dendritic Cells with Differing Metabolic Phenotypes
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家庭静态成熟计划将人类cDC2驱动到一个宽容的状态

Mengmeng Lu1, Runpeng Han1, Hao Yang1

  • 1Department of Otolaryngology, Head and Neck Surgery, Medical Research Institute, Frontier Science Center for Immunology and Metabolism, Zhongnan Hospital of Wuhan University, State Key Laboratory of Virology and Biosafety, Wuhan University, Wuhan 430071, China; Department of Infectious Diseases, Zhongnan Hospital of Wuhan University, Wuhan University, Wuhan 430071, China.

Immunity
|February 19, 2026
PubMed
概括

研究人员发现了一种新的方式,即树突细胞 (DCs) 帮助维持人类的免疫耐受性. 一种特定类型的DC,称为常规状细胞2型 (cDC2s),可以促进调节性T细胞 (Tregs),以防止免疫过度反应.

关键词:
树突细胞是一种树突细胞.家庭静态成熟的成熟.免疫耐受性 免疫耐受性监管性T细胞是什么胸膜流体的淋巴发育蛋白.组织受限的自我抗原.

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