Tgfbr2 缺乏促进胸前大动脉动脉瘤和剖析中的血管光滑肌细胞的线粒体功能障碍

Zhenqing Teng1, Qi Wang1, Yang Zhang2

  • 1Department of Cardiology, First Affiliated Hospital of Xinjiang Medical University, Urumqi, China.

概括

线粒体功能障碍和转化生长因子-β (TGF-β) 信号传递与胸前大动脉动脉瘤和解剖 (TAADs) 有关. 失调的TGF-β信号直接导致线粒体损伤,导致TAADs的进展和血管退化.

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