肠-大脑相互作用的下部和胆道疾病:儿童/青少年
Carlo Di Lorenzo1, Miguel Saps2, Bruno P Chumpitazi3
1Nationwide Children's Hospital, Columbus, Ohio, USA.
Gastroenterology
|February 19, 2026
概括
罗马五项标准更新了小儿肠-大脑相互作用障碍 (DGBI),使用症状模式,而不是年龄. 这次修订引入了新的诊断,并完善了现有的诊断,以提高儿童和青少年的清晰度.
科学领域:
- 儿科胃肠病学 儿科胃肠病学
- 功能性胃肠道疾病 功能性胃肠道疾病
- 肠-大脑相互作用研究研究
背景情况:
- 罗马标准是全球公认的标准,用于对功能性胃肠道疾病进行分类.
- 之前的代依赖于基于年龄的细分,这可能会限制儿科患者的诊断精度.
- 对儿科功能性胃肠道疾病的不断发展的理解需要更新的诊断框架.
研究的目的:
- 提出针对小儿肠脑相互作用 (DGBI) 疾病的更新的"罗马五号标准".
- 引入基于解剖区域和症状模式的新分类系统.
- 为了提高诊断清晰度和指导儿童DGBIs的管理.
主要方法:
- 修订现有标准,以适用于诸如易怒肠综合征和功能性便秘等疾病.
- 引入新的诊断实体,如中心介导的腹部疼痛综合征和婴儿痛苦综合征 (以前称为婴儿结肠).
- 从以年龄为基础的分类重组到以地区和症状为基础的分类.
主要成果:
- 罗马五号标准取代了基于年龄的分类,以一种专注于腹痛,排便/直肠障碍和不适障碍的分类.
- 引入了新的疾病,如胆道疼痛综合征,功能性腹部胀气,以及proctalgia fugax.
- 对刺激性肠综合征,功能性便秘和非保留性便失禁的修订标准提高了诊断的清晰度.
结论:
- 更新的罗马五号标准为儿科DGBI提供了更一致的诊断框架.
- 新的分类旨在改善儿童和青少年肠-大脑相互作用障碍的识别和管理.
- 强调承认DGBI与其他胃肠道疾病的并发症.
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