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甲状腺功能低下症与心房基质负担的关联以及心房的导管切除后的复发

Jose Antonio L Bautista^1,2, Danica Ann D Leycano¹, Naomi P Ong^1,2,3

¹Heart Rhythm Center, Cardiovascular Center, Taipei Veterans General Hospital, Taipei, Taiwan.

Korean circulation journal

|February 19, 2026

概括

甲状腺功能低下症增加了由于更多的触发因素和驱动因素,经过切除后心房动的复发. 它的效果是间接的,这表明改进的映射可能有助于甲状腺功能低下患者.

科学领域:

心脏病学心脏病学
内分泌学在内分泌学.
电子生理学电子生理学

背景情况:

甲状腺功能低下症与增加心房动 (AF) 易感性有关.
了解甲状腺功能低下患者的AF复发因素对于有效的切除策略至关重要.

研究的目的:

确定与AF复发的关联因素. 导管切除后的AF复发.
在甲状腺和甲状腺功能低下个体之间比较心律失常基质和复发率.

主要方法:

对591名接受AF切除术 (2015-2019) 的患者进行了回顾性审查.
甲状腺功能低下和甲状腺功能良好组之间的临床,心声和电生理学参数的比较.
对肺静脉 (PV) 和非PV (NPV) 触发因子,AF驱动因子和复发预测因子的多变Cox回归的分析.

主要成果:

甲状腺功能低下患者 (10.9%) 的高血压率更高,左心脏直径更大,NPV触发因素和AF驱动因素更多.
在甲状腺功能下降组中,AF复发明显高 (44.6%对18.1%).
复发的独立预测因素包括AF驱动器,NPV触发器,LAD,峰值E速度和E/e'比率;甲状腺功能低下的影响是间接的.

结论:

甲状腺功能低下症与心房触发器,驱动器和AF复发的增加有关.
甲状腺功能低下症对复发的影响很可能是由于间接的结构和心律失常性重塑.
综合性驱动器映射可能会增强甲状腺功能低下患者的切除结果,需要前性验证.

关键词:

心房动是一种心房动.导管切除导管切除导管切除导管切除甲状腺功能低下症甲状腺功能低下症

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