低聚醇含量处于超加工食品消费和低级炎症之间的路径上:来自Moli-sani研究的横截面分析
Emilia Ruggiero1, Augusto Di Castelnuovo1, Simona Costanzo2
1Research Unit of Epidemiology and Prevention, IRCCS NEUROMED, Pozzilli, IS, Italy.
超加工食品 (UPF) 与炎症有关,部分原因是它们含有较少的多. 减少UPF摄入量和吃更多富含多的食物可能会降低炎症和慢性疾病风险.
科学领域:
- 营养科学 营养科学
- 饮食流行病学 饮食流行病学
- 炎症研究 炎症研究
背景情况:
- 低级炎症是一种潜在的机制,可以将超加工食品 (UPF) 与不良健康结果联系起来.
- UPF的特点是营养价值低,缺乏生物活性化合物,如多.
- 这项研究调查了低聚醇含量是否调解了UPF和炎症之间的关联.
研究的目的:
- 测试低聚醇含量调解了UPF消费和低级炎症之间的联系的假设.
- 量化饮食中的多在UPF和炎症之间的关联中的作用.
- 为减少炎症和慢性疾病风险提供饮食建议.
主要方法:
- 分析了22169名参与Moli-sani研究 (2005-2010) 的数据.
- 使用Phenol-Explorer数据库估计总多摄入量.
- 使用Nova分类对UPF进行分类,并通过INFLA评分对低级炎症进行评估.
主要成果:
- 较高的UPF摄入量与饮食中的多醇含量显著降低相关 (β = -132.3 mg/d).
- 增加的UPF消耗与更高的INFLA得分相关,表明较大的低级炎症 (β = 0.23).
- 饮食中的多解释了UPF和炎症之间的18%的关联,干解释了32.6%.
结论:
- 较高的UPF消费与较低的饮食中聚烯摄入量有关.
- UPFs的低聚醇含量显著促进了它们与轻度炎症的关联.
- 建议限制UPF摄入量并增加富含多的食物的消费,以减轻炎症和慢性疾病风险.
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