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Updated: Feb 21, 2026

gDNA Enrichment by a Transposase-based Technology for NGS Analysis of the Whole Sequence of BRCA1, BRCA2, and 9 Genes Involved in DNA Damage Repair
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gDNA Enrichment by a Transposase-based Technology for NGS Analysis of the Whole Sequence of BRCA1, BRCA2, and 9 Genes Involved in DNA Damage Repair

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在携带BRCA1或BRCA2致病性生殖系变异的携带者中向性前列腺癌查检测出临床相关的疾病:IMPACT研究的5年结果

Elizabeth K Bancroft1, Elizabeth C Page2, Jana McHugh2

  • 1Oncogenetics Team, Genetics and Epidemiology, The Institute of Cancer Research, London, UK; Cancer Genetics Unit and Academic Urology Unit, The Royal Marsden NHS Foundation Trust, London, UK.

European urology
|February 19, 2026
PubMed
概括

在患有BRCA1/BRCA2病原性生殖系变异 (PGVs) 的男性中,使用PSA查前列腺癌 (PC) 发现BRCA2载体中临床显著PC的比率较高. 在BRCA1携带者中也发现了相关瘤的早期检测.

关键词:
这就是BRCA1的原因.这就是BRCA2的原因.癌症查 癌症查前列腺癌是什么意思 前列腺癌是什么意思前列腺特异性抗原前列腺特异性抗原

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