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-90放射栓塞作为肝膜黑色素瘤转移的安全和有效治疗选择

Jason R Ni¹, Matthew Quirk¹, Bartosz Chmielowski²

¹Division of Interventional Radiology, Department of Radiology, David Geffen School of Medicine, University of California Los Angeles, 757 Westwood Plaza, Suite 2125, Los Angeles, CA, 90095, USA.

Cardiovascular and interventional radiology

|February 19, 2026

概括

-90 (Y) 放射性栓塞是一种安全有效的治疗方法,用于肝膜黑色素瘤转移. 放射细分切除术显示这些患者的放射反应和疾病控制率很高.

科学领域:

肝胆瘤学肝胆瘤学
干预性放射学是干预性的放射学.
核医学是一种核医学.

背景情况:

卵巢黑色素瘤经常转移到肝脏.
肝转移严重影响患者的预后.
对于肝膜性黑色素瘤,有效的治疗选择有限.

研究的目的:

评估伊-90 (Y) 放射栓塞对肝皮膜黑色素瘤转移的安全性和有效性.
为了在这个患者群体中比较细分切除与叶片放射栓塞.

主要方法:

对25名肝膜黑色素瘤转移患者进行了回顾性研究,这些患者接受了90Y放射栓塞治疗.
收集的数据包括瘤特征,治疗细节,毒性,存活率和成像反应 (RECIST标准).
分析的重点是放射性反应,疾病控制,无进展生存率和整体生存率.

主要成果:

90Y放射栓塞实现了94%的放射性反应率 (完全或部分).
分段切除术显示显著更高的完整放射性反应率 (78%) 与叶膜放射栓塞 (35%) 相比.
中位数无进展生存时间为8.0个月,中位数整体生存时间为20.3个月,一年生存率为76%.

结论:

90Y放射栓塞是一种安全有效的治疗肝皮膜黑色素瘤.
辐射分段切除术特别有效,可以达到高的放射性反应和疾病控制率.
[90]Y放射栓塞为治疗状黑色素瘤的肝转移提供了一个有前途的治疗选择.

关键词:

肝转移是发生在肝脏中的转移.选择性的内部辐射疗法.在Uveal黑色素瘤.-90的放射性栓塞是因为-90的放射性栓塞.

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