昆虫载体耐受性对一种新类杀虫剂的病毒媒介变化
Max Schmidtbauer1, Jordan Withycombe1,2, Jinlong Han1
1Department of Agricultural Biology, Colorado State University, Fort Collins, CO, USA.
Scientific reports
|February 19, 2026
概括
甜菜卷曲顶部病毒 (BCTV) 感染增强了甜菜叶 (BLH) 对类杀虫剂的生存率. 这种病毒介导的耐受性与昆虫基因表达的变化有关,而不是行为.
科学领域:
- 植物病毒学 植物病毒学
- 昆虫学 昆虫学是一门学科.
- 杀虫剂毒理学 杀虫剂毒理学
背景情况:
- 甜菜卷曲顶部病毒 (BCTV) 在美国西部造成了大量的甜菜作物损害.
- BCTV是由甜菜叶 (BLH) 传播的,这种载体主要使用杀虫剂进行管理.
- 植物病毒可以改变载体生物学和行为,以增强传播.
研究的目的:
- 为了研究BCTV感染如何影响BLH生存,当暴露于杀虫剂.
- 探索BLH中病毒媒介杀虫剂耐受性背后的分子机制.
主要方法:
- 病毒性BLHs (BCTV感染者) 和非病毒性BLHs均用不同度的新烟类杀虫剂和类杀虫剂进行治疗.
- 在感染和未感染组之间比较了昆虫的存活率.
- 对BLHs进行了转录组分析 (RNA测序),这些BLHs被暴露在次致命的尼可类药物剂量中.
主要成果:
- 病毒性BLHs显示对亚致命的尼尼科丁类药物的存活率增加,但不是铁类药物.
- 转录组分析显示,BCTV感染BLHs的排毒,免疫和与压力相关的基因受到上调调节.
- 与运动和皮层结构相关的基因被下调,这表明没有对抗虫剂耐受性的行为适应.
结论:
- 在BLHs中,BCTV感染会产生耐受性,这种耐受性是由昆虫的分子变化所介导的.
- 这种耐受性很可能是由于增强的解毒和应激反应途径,而不是行为修改.
- 研究结果提供了关于载体-宿主-病原体相互作用和抗昆虫剂机制的见解.
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