相关实验视频

Updated: Jul 24, 2026

Use of Viral Entry Assays and Molecular Docking Analysis for the Identification of Antiviral Candidates against Coxsackievirus A16
06:03

Use of Viral Entry Assays and Molecular Docking Analysis for the Identification of Antiviral Candidates against Coxsackievirus A16

Published on: July 15, 2019

选择植物生物活性化合物的抗HCVNS2-3潜力通过对接,模拟和DFT揭示

Clement I Mboto1,2, Elizabeth N Mbim2,3, Uwem O Edet4,5

  • 1Department of Microbiology, Faculty of Biological Science, University of Calabar, Calabar, Cross River State, Nigeria.

Scientific reports
|February 19, 2026
PubMed
概括

研究人员探索了来自Jatropha tanjorensis和Solanum nigrum的天然化合物,用于治疗C型肝炎病毒 (HCV). 这些化合物没有表现出毒性,并且与HCV NS2-3蛋白质有良好的结合,这表明它们可能是更安全的替代品.

关键词:
这种植物包括Jatropha tanjorensis和Solanum nigrum.生物活性化合物 生物活性化合物在 DFT 方面,它是最重要的.在HCV病毒感染的过程中,分子对接是分子对接.模拟模拟是为了模拟.

更多相关视频

Quantitative Structure-Activity Relationship, Activity Prediction, and Molecular Dynamics of Non-nucleotide Reverse Transcriptase Inhibitors10:29

Quantitative Structure-Activity Relationship, Activity Prediction, and Molecular Dynamics of Non-nucleotide Reverse Transcriptase Inhibitors

Published on: May 9, 2025

Application of I TASSER, trRosetta, UCSF Chimera, HADDOCK server, and HEX loria for De Novo and In Silico Design of Proteins05:08

Application of I TASSER, trRosetta, UCSF Chimera, HADDOCK server, and HEX loria for De Novo and In Silico Design of Proteins

Published on: July 8, 2025

相关概念视频

π Electron Effects on Chemical Shift: Aromatic and Antiaromatic Compounds01:14

π Electron Effects on Chemical Shift: Aromatic and Antiaromatic Compounds

In aromatic compounds, such as benzene, the circulation of (4n + 2) π-electrons sets up a diamagnetic or diatropic ring current around the perimeter of the molecule. This current induces a magnetic field that opposes the external field inside the ring and reinforces it on the outside. The protons in benzene are deshielded and exhibit high chemical shifts in the range 6.5–8.5 ppm. The shielding effect at the center of the ring is evident in complex aromatic molecules, such as annulenes. In...
Local Anesthetics: Chemistry and Structure-Activity Relationship01:30

Local Anesthetics: Chemistry and Structure-Activity Relationship

Local anesthetics (LAs) are drugs that induce a temporary loss of sensation in a limited body area, preventing pain. Cocaine was the first local anesthetic discovered in the late 19th century. Cocaine is a benzoic acid ester obtained from the leaves of coca shrubs and was often used for its psychotropic effects. Cocaine was first isolated in 1860 by Albert Niemann. Sigmund Freud studied the physiological actions of cocaine. Carl Koller later introduced it into clinical practice in 1884 as a...