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Updated: Feb 21, 2026

Examining BCL-2 Family Function with Large Unilamellar Vesicles
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Published on: October 5, 2012

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BCL-2 的作用是什么? 从新的分子见解到临床影响

Carlo M Croce1, Stephen W G Tait2,3, Ana J Garcia-Sáez4,5

  • 1Department of Cancer Biology and Genetics and Comprehensive Cancer Center, The Ohio State University, Columbus, OH, USA. Carlo.Croce@osumc.edu.

Cell death and differentiation
|February 19, 2026
PubMed
概括

几十年来对BCL-2家族蛋白质的研究导致了BCL-2抑制剂的开发,通过向细胞亡来彻底改变癌症治疗. 了解抵抗机制和探索新的治疗途径是癌症治疗未来进展的关键.

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