散播性血清瘤:在ROSE的一项不寻常的发现
Erika E Doxtader1, Jona Banzon2, Sanjay Mukhopadhyay1
1Department of Pathology, Diagnostics Institute, Cleveland Clinic, Cleveland, Ohio, USA.
Diagnostic cytopathology
|February 19, 2026
概括
在EBUS-TBNA期间进行快速现场评估可以在移植患者中表明散布性基因质. 常规污点上的细胞形态学为这种真菌感染提供了早期诊断线索.
科学领域:
- 医学诊断 医学诊断 医学诊断
- 传染性疾病 传染性疾病
- 肺部病理学 肺部病理学
背景情况:
- 传播性基因质菌是一种严重的真菌感染,特别是在免疫受损的个体中.
- 接受移植的接受者由于免疫抑制而面临更高的风险.
- 早期诊断对于有效的管理和改善患者结果至关重要.
研究的目的:
- 报告一个不寻常的传播性基因质菌病例.
- 突出快速现场评估 (ROSE) 在内支气管超声波导向跨支气管针吸收 (EBUS-TBNA) 期间对疑似散布性基因质粒体病的有用性.
- 强调细胞形态学发现在早期诊断中的作用.
主要方法:
- 一个移植接受者出现相关症状的案例研究.
- 针对中枢淋巴结的EBUS-TBNA的性能 (11L和7号站).
- 程序内ROSE用于立即的细胞形态评估.
主要成果:
- 在EBUS-TBNA程序中,ROSE建议在EBUS-TBNA过程中传播了他的血形成.
- 随后的微生物学培养证实了传播性基因质菌的诊断.
- 常规染料上的细胞形状特征表明真菌感染.
结论:
- 在EBUS-TBNA期间的ROSE可以及时提供传播性细胞质的诊断怀疑.
- 常规污点上的细胞形态学是识别散布性基因质瘤的一个有价值的工具.
- 及时诊断和治疗对于控制移植患者这种机会性感染至关重要.
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