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美国抗微生物耐药性实验室网络的Candida auris测试,2022-2023年
Emerging infectious diseases
|February 19, 2026
概括
在Candida auris中抗菌素耐药性是一个主要问题. 在2022-2023年,美国95%的经过测试的Candida auris分离物显示出对可纳的耐药性,这突显了需要更好的实验室测试的需要.
科学领域:
- 临床微生物学 临床微生物学
- 传染病 传染病 传染病
- 抗微生物耐药性 抗微生物耐药性
背景情况:
- 黄是一种新兴的多抗药性真菌病原体.
- 增加的Candida auris感染率构成了重大的公共卫生挑战.
- 准确的实验室鉴定和敏感性测试对于患者管理至关重要.
研究的目的:
- 评估美国Candida auris临床分离物的抗真菌耐药性模式.
- 评估Candida auris对关键抗真菌剂的耐药性目前的情况.
主要方法:
- 抗微生物耐药性实验室网络 (ARLN) 分析了8033种Candida auris.的临床分离物.
- 对可纳,安福特瑞辛B和类进行了抗真菌敏感性测试.
主要成果:
- 观察到流可纳耐药性的高患病率 (95%).
- 在15%的隔离物中观察到对安福特里辛B的耐药性.
- 埃奇诺坎丁耐药性相对较低,影响1%的隔离物.
结论:
- 在美国,Candida auris对可纳具有广泛的耐药性.
- 提高Candida auris识别和抗真菌敏感性测试的实验室能力至关重要.
- 应对这种威胁需要持续的监视和改进的诊断能力.
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