低强度冲击波治疗对勃起功能和勃起功能障碍男性阴茎血管参数的影响:随机对照研究的系统审查和元分析
Selahittin Cayan1,2, Germar Michael Pinggera2,3, Hiva Alipour2,4
1Department of Urology, University of Mersin School of Medicine, Mersin, Türkiye.
The world journal of men's health
|February 20, 2026
概括
低强度冲击波疗法 (LiSWT) 在勃起功能障碍 (ED) 的男性中适度改善勃起功能得分. 然而,LiSWT并没有显著改变其他功能或血管参数,这限制了其在常规ED治疗中的临床相关性.
科学领域:
- 泌尿器科 泌尿器科 泌尿器科 泌尿器科
- 安德罗学与人类学
- 再生医学是一种再生医学.
背景情况:
- 勃起功能障碍 (ED) 是一种影响男性健康的普遍疾病.
- 低强度冲击波疗法 (LiSWT) 已成为ED的潜在治疗方法.
- 评估LiSWT对勃起功能和阴茎血液动力学的疗效至关重要.
研究的目的:
- 系统地审查和元分析关于ED治疗LiSWT的随机对照试验 (RCT).
- 评估LiSWT对勃起功能 (EF) 和阴茎血管参数的影响.
- 为了比较LiSWT的结果与假药或没有治疗的对照.
主要方法:
- 对Scopus,PubMed和Cochrane数据库进行系统的文献搜索.
- 纳入评价ED男性LiSWT的RCT.
- 主要结果:国际勃起功能指数 (IIEF) -5和IIEF-EF域得分. 二次结局:勃起硬度得分 (EHS),性行为概况 (SEP) Q2/Q3,全球评估问题 (GAQ) 和阴茎多普勒超声参数 (PSV,EDV,RI).
主要成果:
- 对12项研究的聚合分析显示,IIEF-5 (SMD,1.19) 和IIEF-EF (SMD,1.24) 评分显著改善,有利于LiSWT.
- 在EHS,SEP Q2/Q3,GAQ得分或阴茎多普勒参数 (PSV,EDV,RI) 之间没有发现显著差异. LiSWT和对照组之间.
- LiSWT在勃起功能得分方面表现出适度的好处,但在其他评估参数方面没有.
结论:
- 对于ED的男性来说,LiSWT在IIEF分数中提供了适度的改善.
- 治疗没有产生其他功能或血管参数的显著变化,这表明对大多数患者的临床相关性有限.
- 目前的证据不支持在ED治疗算法中常规使用LiSWT;需要进一步研究来确定响应的患者子组.
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