相关实验视频

Updated: Jun 25, 2026

Implantation and Monitoring by PET/CT of an Orthotopic Model of Human Pleural Mesothelioma in Athymic Mice

Implantation and Monitoring by PET/CT of an Orthotopic Model of Human Pleural Mesothelioma in Athymic Mice

Published on: December 21, 2019

基于FDG和FAPIPET的响应评估减少剂量尼沃卢马布在多间皮瘤:一个案例报告

Morten Bentestuen^1,2, Anne H Thostrup^1,2, Weronika M Szejniuk^2,3

¹Department of Nuclear Medicine and Clinical Cancer Research Centre, Aalborg University Hospital, Aalborg, Denmark.

Clinical physiology and functional imaging

|February 20, 2026

概括

这一案例研究表明,尼沃卢马布免疫疗法可以使患有瘤性多层甲骨瘤的患者受益,即使剂量减少. 像PET/CT这样的先进成像技术有效评估了治疗反应.

科学领域:

在瘤学瘤学.
放射学放射学是一门学科.
免疫治疗是一种免疫疗法.

背景情况:

客观反应评估对于接受免疫治疗的肺部间皮瘤患者至关重要.
瘤性多性骨间皮瘤是一种侵略性的亚型,需要有效的治疗策略.

研究的目的:

报告一个用nivolumab治疗的sarcomatoid 膜间皮瘤患者.
为了比较CT,[18F]FDG PET/CT和[68Ga]Ga-FAPI PET/CT在评估治疗反应中的疗效.

主要方法:

一名75岁的男性患者患有肉类质性膜间皮瘤,由于过敏反应,接受了降低剂量的nivolumab.
在治疗前和治疗后进行了包括CT,[18F]FDG PET/CT和[68Ga]Ga-FAPI PET/CT在内的连续成像.

主要成果:

患者经历了显著的临床益处,尽管降低了尼沃卢马布剂量.
随访成像显示了所有模式的显著形态和代谢改善.
[18F]FDG PET/CT和[68Ga]Ga-FAPI PET/CT在响应评估中表现出互补的作用.

结论:

尼沃卢马布免疫疗法可以有效治疗瘤性多叶膜间皮瘤,即使用剂量修改.
结合CT和先进的PET/CT技术,可以全面评估治疗反应.
这一案例凸显了[68Ga]Ga-FAPI PET/CT作为中皮瘤中新型成像生物标志物的实用性.

关键词:

这就是为什么CTCTCTCTCTCT FAPIAPI FAPIAPI 这是一个很好的方法.德国联邦航空公司 (FDG)在这里,PET是PET.胸腔间皮瘤 (PLEURAL MESOTHELIOMA) 是一种多发性中皮瘤.响应评估响应评估响应评估

更多相关视频

An Automated Radiosynthesis of [68Ga]Ga-FAPI-46 for Routine Clinical Use

An Automated Radiosynthesis of [⁶⁸Ga]Ga-FAPI-46 for Routine Clinical Use

Published on: May 24, 2024

Automated Preparation of [68Ga]Ga-3BP-3940 on a Synthesis Module for PET Imaging of the Tumor Microenvironment

Automated Preparation of [⁶⁸Ga]Ga-3BP-3940 on a Synthesis Module for PET Imaging of the Tumor Microenvironment

Published on: April 25, 2025

相关概念视频

Positron Emission Tomography

Positron Emission Tomography

Positron emission tomography (PET) is a medical imaging technique involving radiopharmaceuticals — substances that emit short-lived radiation. Although the first PET scanner was introduced in 1961, it took 15 more years before radiopharmaceuticals were combined with the technique and revolutionized its potential.
One of the main requirements of a PET scan is a positron-emitting radioisotope, which is produced in a cyclotron and then attached to a substance used by the part of the body being...

Radiological Investigation III: Pulmonary Angiogram and PET Scan

Radiological Investigation III: Pulmonary Angiogram and PET Scan

Radiological investigations are paramount in the diagnosis and management of various pulmonary diseases. Two essential investigations are the Pulmonary Angiogram and the Positron Emission Tomography (PET) Scan.
Pulmonary Angiogram
A Pulmonary Angiogram is an invasive procedure involving injecting a contrast medium through a catheter threaded into the pulmonary artery or the right side of the heart to visualize the pulmonary vasculature. Computed Tomography (CT) scans have mainly replaced this...