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Updated: Feb 21, 2026

Development and Maintenance of a Preclinical Patient Derived Tumor Xenograft Model for the Investigation of Novel Anti-Cancer Therapies
09:29

Development and Maintenance of a Preclinical Patient Derived Tumor Xenograft Model for the Investigation of Novel Anti-Cancer Therapies

Published on: September 30, 2016

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向炎症和瘤途径:环氧酶-2,表皮生长因子受体,和p38基因激活蛋白激酶抑制由pyrazolone衍生物

Sevde Nur Biltekin Kaleli1,2, Evren Önay Uçar3, Zafer Şahin4,5

  • 1Department of Pharmaceutical Microbiology, School of Pharmacy, Medipol University, Istanbul, Türkiye.

ChemMedChem
|February 20, 2026
PubMed
概括

合成了八种新的皮拉佐衍生物,并对其抗炎症和抗癌性质进行了评估. 化合物7和8选择性抑制循环氧化酶-2 (COX-2),显示出作为抗炎和抗癌剂的潜力.

关键词:
这是一种抗癌药物.这是一种抗炎药,是一种抗炎药.皮肤上生长因子受体.p38 基因激活蛋白激酶的作用皮拉佐隆 (pyrazolone) 是一种类型的

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