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Updated: Jul 3, 2026

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NRG4通过ERBB4-YAP1-介导的MMPs下调来抑制乳腺癌转移

Saijun Wang1, Mingwei Guo2, Lingyun Xu3

  • 1Department of Gastrointestinal Surgery, Changzhou Medical Center, The Third Affiliated Hospital of Nanjing Medical University, The Affiliated Changzhou No.2 People's Hospital of Nanjing Medical University, Nanjing Medical University, Changzhou, Jiangsu 213000, China.

Genes & diseases
|February 20, 2026
PubMed
概括

肥胖加剧了乳腺癌的传播. 来自脂肪组织的神经调节素4 (NRG4) 通过阻断ERBB4-YAP1通路,作为转移抑制剂,提供潜在的治疗标.

关键词:
乳腺癌是什么? 乳腺癌是什么?皮质介质酶过渡 皮质介质过渡矩阵金属蛋白酶的改变神经调节素 4 神经调节素 4哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈

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