嵌入大型瘤的状神经纤维瘤的不寻常呈现:一个病例报告
Waseem Alhawsawi1, Wafa Alghamdi1, Maria AlSulami2
1King Fahad Armed Forces Hospital, Jeddah, Saudi Arabia.
Case reports in dermatology
|February 20, 2026
概括
本病例报告详细介绍了神经纤维瘤1型神经纤维瘤 (NF1) 患者的一种不寻常的plexiform神经纤维瘤 (PNF),其特征是巨大的骨. 这种罕见的皮肤病呈现突显了对非典型NF1表现的认识的必要性.
科学领域:
- 皮肤病学 皮肤病学
- 在瘤学瘤学.
- 遗传学 是一个遗传学.
背景情况:
- Plexiform 神经纤维瘤 (PNFs) 是与神经纤维瘤类型 1 (NF1) 相关的良性瘤.
- NF1是一种由NF1基因突变引起的遗传性疾病,导致Ras信号失调和不受控制的细胞生长.
- PNF可以涉及广泛的神经并具有恶性潜力.
研究的目的:
- 报告一个不寻常的plexiform神经纤维瘤病例,呈现出大型骨.
- 提高对神经纤维素炎1型患者非典型皮肤病症状的认识.
主要方法:
- 一个42岁的男性患有NF1.1的病例报告.
- 许多神经纤维瘤的临床表现,咖啡牛奶斑点和尾斑点.
- 详细描述一个大型PNF具有显着的状结构.
主要成果:
- 在下背部的一个大型状神经纤维瘤 (10 × 15厘米) 呈现出一种"袋子"的感觉.
- 在PNF中包含多个大型彗星 (0.5×0.5厘米).
- 由于临床一致性和患者拒绝,并没有进行组织病理学确认.
结论:
- 这种病例呈现出以前未报告的PNF表现,具有大型瘤.
- 强调了对非典型NF1表现的彻底临床评估的重要性.
- 强调需要认识到罕见的皮肤病发现,以防止误诊,并确保适当的患者管理.
相关概念视频
01:11Papillary Dermis
6.2K
Dermis
The dermis might be considered the "core" of the integumentary system, as distinct from the epidermis and hypodermis. It contains blood and lymph vessels, nerves, and other structures, such as hair follicles and sweat glands. The dermis is made of two layers of connective tissue that comprise an interconnected mesh of elastin and collagenous fibers, produced by fibroblasts.
Papillary Layer
The papillary layer is made of loose, areolar connective tissue, which means the collagen...
The dermis might be considered the "core" of the integumentary system, as distinct from the epidermis and hypodermis. It contains blood and lymph vessels, nerves, and other structures, such as hair follicles and sweat glands. The dermis is made of two layers of connective tissue that comprise an interconnected mesh of elastin and collagenous fibers, produced by fibroblasts.
Papillary Layer
The papillary layer is made of loose, areolar connective tissue, which means the collagen...
6.2K
01:30Skin Cancer
6.2K
Skin cancer is a type of cancer that occurs when there is an abnormal growth of skin cells, usually triggered by damage to the DNA within the skin cells. It is primarily caused by exposure to ultraviolet (UV) radiation from the sun or artificial sources like tanning beds. Skin cancer is the most common type of cancer worldwide, and its incidence continues to rise.
Basal Cell Carcinoma (BCC): BCC is the most common type of skin cancer, accounting for about 80% of cases. It typically develops in...
Basal Cell Carcinoma (BCC): BCC is the most common type of skin cancer, accounting for about 80% of cases. It typically develops in...
6.2K
02:23Abnormal Proliferation
5.3K
Under normal conditions, most adult cells remain in a non-proliferative state unless stimulated by internal or external factors to replace lost cells. Abnormal cell proliferation is a condition in which the cell's growth exceeds and is uncoordinated with normal cells. In such situations, cell division persists in the same excessive manner even after cessation of the stimuli, leading to persistent tumors. The tumor arises from the damaged cells that replicate to pass the damage to the...
5.3K
01:15Reticular Dermis
5.0K
The papillary and reticular dermis are the two layers of the dermis. They are made of connective tissue with fibers of collagen extending from one to the other, making the border between the two somewhat indistinct. The dermal papillae extending into the epidermis belong to the papillary layer, whereas the dense collagen fiber bundles below belong to the reticular layer.
Reticular Layer
Underlying the papillary layer is the much thicker reticular layer, composed of dense, irregular connective...
Reticular Layer
Underlying the papillary layer is the much thicker reticular layer, composed of dense, irregular connective...
5.0K