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在急性缺血性中风后的血红素和3个月后的结果之间非线性关联:在男性中确定值效应

Xiaomin Liang¹, Qian Wang², Zemao Xing¹

¹Department of Critical Care Medicine, Shenzhen Second People's Hospital, The First Affiliated Hospital of Shenzhen University, Shenzhen, Guangdong, China.

Frontiers in medicine

|February 20, 2026

概括

血红素 (HCT) 水平显示出与急性缺血性中风 (AIS) 患者的结果的性别特异性联系. 较低的HCT在男性中与减少的不良结果相关,但在女性中没有发现这种联系.

科学领域:

神经学神经学
血液学血液学血液学
流行病学流行病学

背景情况:

急性缺血性中风 (AIS) 是全球主要的死亡和残疾原因.
血红素 (HCT) 水平,代表红细胞比例,与AIS结果有着争论的关联.
了解影响AIS预后的因素,包括HCT,对于患者管理至关重要.

研究的目的:

调查韩国AIS患者血红素 (HCT) 水平与3个月不良结果之间的关联.
在AIS中探索HCT-结果关系中的潜在性别差异.
确定与AIS预后相关的特定HCT值.

主要方法:

韩国一项针对1896名AIS患者的前性队列研究的二次分析.
血红素 (HCT) 分析为连续变量和四分位数.
逻辑回归和通用添加模型用于评估HCT和3个月不良结果之间的非线性关系 (修改的兰金度量评分≥3),用性别分层分析.

主要成果:

总共分析了1896名AIS患者 (61.34%是男性).
在整体和男性中观察到HCT与不良结果之间的非线性关系,较低的HCT水平 (总体<34.4%,男性<36.4%) 与风险降低有关.
在女性AIS患者中,没有发现HCT和不良结果之间的显著关联.

结论:

在AIS患者中,HCT和3个月后的结果之间存在非线性,性别特定的关系.
在男性患者中,较低的HCT水平与不良结果相反相关.
在女性患者的HCT水平和不良结果之间没有发现显著的关联.

关键词:

急性缺血性中风是急性缺血性中风.血中位数是什么意思血中位数是什么意思非线性关系是一种非线性关系.二次分析二次分析二次分析值效应是一个值效应.

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