COVID-19引起的嗅觉功能障碍对营养的影响
Elizabeth M Mastoloni1, Aaron Tucker1, Evan French2
1Department of Otolaryngology-Head & Neck Surgery Virginia Commonwealth University School of Medicine Richmond Virginia USA.
OTO open
|February 20, 2026
概括
与COVID-19相关的嗅觉丧失 (无味症) 显著增加患营养过剩和一般营养不良的风险. 这一发现凸显了COVID-19中康复的患者面临的关键营养挑战.
科学领域:
- 营养科学 营养科学
- 传染病流行病学 传染病流行病学
- 公共卫生 公共卫生
背景情况:
- 营养和化学感知知觉之间存在着确定的联系.
- 与COVID-19相关的化学感官功能障碍的营养后果在很大程度上仍然没有特征.
- COVID-19经常导致嗅觉功能障碍,影响味觉和嗅觉.
研究的目的:
- 为了调查COVID-19诱导的厌氧和随后的营养不良之间的关联.
- 量化COVID-19相关嗅觉丧失的个体中过度营养,营养不良和任何营养不良诊断的风险.
主要方法:
- 使用国家COVID队列协作 (N3C) 数据库进行回顾性队列研究.
- 纳入标准:没有先前营养不良诊断的COVID-19阳性成年人.
- 统计分析涉及几率比率 (OR) 计算与95%的置信区间 (CI).
主要成果:
- 分析了一组19384名COVID-19阳性成年人,他们患有新发性厌氧症.
- 观察到过度营养的几率显著增加 (OR 1.36,95% CI [1.26,1.46]).
- 发现任何营养不良诊断的几率显著增加 (OR 1.34,95% CI [1.25,1.44]),但营养不良不是 (OR 0.88,95% CI [0.66,1.16]).
结论:
- 在COVID-19感染后的化学传感损失,特别是厌氧症,与随后过度营养的风险增加有关.
- 这些发现表明,国家范围内的公共卫生问题涉及COVID-19后人口的营养不平衡.
- 进一步的研究是有必要的,以了解机制,并制定干预措施,以营养支持受影响的个体.
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