晚期胃食道结腺癌与皮肤参与:一个多学科的视角
Kholoud Alqasem1, Sakhr Alshwayyat2,3,4, Salsabeel Aljawabrah5
1Department of Internal Medicine, King Hussein Cancer Center, Amman, Jordan.
Oxford medical case reports
|February 20, 2026
概括
胃食道结腺癌很少扩散到皮肤,这表明预后不佳. 这一案例凸显了管理这种癌症的侵袭性皮肤转移的挑战.
科学领域:
- 在瘤学瘤学.
- 胃肠病学 胃肠病学
- 皮肤病学 皮肤病学
背景情况:
- 来自内脏恶性瘤的皮肤转移很少见,并且与预后不佳有关.
- 胃食道结 (GEJ) 腺癌是皮肤转移的一个罕见原因.
- 这一案例突出了GEJ腺癌与皮肤转移的管理挑战.
研究的目的:
- 报告一个罕见的GEJ腺癌与皮肤转移的病例.
- 讨论处理此类案件的挑战.
- 为了强调GEJ腺癌与皮肤转移的侵略性.
主要方法:
- 一个63岁的男性患有IV期Siewert 3 GEJ腺癌的病例报告.
- 记录了最初的广泛皮肤转移.
- 尽管有息性辐射,FOLFOX,FOLFIRI和税疗法,但病情的详细进展.
主要成果:
- 患者呈现了GEJ腺癌的广泛皮肤转移.
- 化疗方案 (FOLFOX,FOLFIRI,taxanes) 和辐射疗法没有效果.
- 疾病的进展发生在广泛的转移中,导致肠道穿孔导致死亡.
结论:
- 来自GEJ腺癌的皮肤转移意味着侵袭性疾病和化疗耐药性.
- 管理需要多学科的方法,包括息治疗.
- 对于这些具有挑战性的病例,需要新的治疗策略.
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