饮食炎症指数与乳腺癌风险之间的关联:更新的系统性审查和元分析
Chaoyang Wang1, Qian Zhou1, Liang Chen1
1General Medical 3201 Hospital, Hanzhong, Shaanxi, China.
Frontiers in nutrition
|February 20, 2026
概括
更高的饮食炎症指数 (DII) 与乳腺癌 (BC) 风险增加有关. 采用富含水果,蔬菜和健康脂肪的抗炎饮食对于BC预防和管理至关重要.
科学领域:
- 营养科学 营养科学
- 在瘤学瘤学.
- 流行病学 流行病学
背景情况:
- 饮食对癌症的发展和进展起着重要作用.
- 饮食炎症指数 (DII) 量化了饮食的炎症潜力.
- 了解DII与乳腺癌 (BC) 的关联对于公共卫生至关重要.
研究的目的:
- 进行元分析,澄清DII和BC风险之间的关系.
- 为BC的初级预防和二级管理策略提供证据.
主要方法:
- 在PubMed,Embase,Web of Science和Cochrane图书馆进行系统搜索,截至2025年9月30日.
- 包括观察性研究 (病例控制,队列) 报告DII/E-DII与BC风险或结果的关联.
- 使用随机效应模型进行聚合效应大小,并进行异质性和偏差评估.
主要成果:
- 在元分析中包括了19项研究 (14个病例控制,5个队列).
- 较高的DII分数与BC风险增加有显著的关联 (合并OR=1.91,合并HR=1.08).
- 每增加1个单位的DII与BC风险增加约2%相关,在绝经前和绝经后的妇女中观察到.
结论:
- 由较高的DII分数表明的促炎性饮食模式与BC风险增加有关.
- 促进抗炎饮食 (水果,蔬菜,全谷物,健康脂肪) 对于BC预防和管理很重要.
相关概念视频
Cancer Prevention
6.5K
Several factors can increase the risk of cancer in an individual. About 50% of cancer cases can be prevented by adopting a healthy lifestyle, regular exercise, eating healthy, and following a modest cancer prevention diet. Epidemiological studies have consistently shown that populations with vegetable and fruit-rich diets have reduced the incidence of cancer. On the other hand, populations who have a diet rich in animal fat, red meat, junk food, or high calories are predisposed to cancer.
Some...
Some...
6.5K
Inflammatory Bowel Disease III: Diagnostic Studies and Management I-Nutritional Therapy
1.1K
Various diagnostic tests are employed in the diagnostic process for Inflammatory Bowel Disease (IBD), particularly to differentiate between Crohn's disease and ulcerative colitis.
Diagnostic studies
A colonoscopy is the definitive screening test, distinguishing ulcerative colitis from other colon diseases with similar symptoms. During a colonoscopy test, inflamed mucosa with exudate ulcerations can be observed, and biopsies are taken to determine the histologic characteristics of the...
Diagnostic studies
A colonoscopy is the definitive screening test, distinguishing ulcerative colitis from other colon diseases with similar symptoms. During a colonoscopy test, inflamed mucosa with exudate ulcerations can be observed, and biopsies are taken to determine the histologic characteristics of the...
1.1K
Psychoneuroimmunology: Diabetes and Cancer
531
Chronic stress has been linked to both the onset and progression of serious health conditions, including Type 2 diabetes and cancer. Type 2 diabetes, a widespread chronic illness, is closely associated with obesity and insulin resistance, both of which often worsen under stress. Studies indicate that men experiencing high levels of chronic stress face a 45% higher risk of developing diabetes compared to those with minimal stress. Stress triggers physiological responses that elevate blood...
531
Inflammatory Bowel Disease I: Introduction
42
Inflammatory bowel disease is a group of chronic disorders marked by recurrent inflammation of the gastrointestinal tract due to an abnormal immune response against gut microflora. This leads to tissue damage. The two main forms are Crohn’s disease and ulcerative colitis.Crohn’s DiseaseCrohn’s disease is a relapsing inflammatory disorder that can affect any part of the GI tract, from the mouth to the anus. It involves all layers of the bowel wall (transmural) and shows...
42
Inflammatory Bowel Disease III: Crohn's Disease
35
Crohn’s disease is a chronic, relapsing form of inflammatory bowel disease characterized by segmental, transmural inflammation that can affect any part of the gastrointestinal tract. Its pathogenesis arises from a combination of genetic susceptibility, environmental exposures, epithelial barrier dysfunction, and immune dysregulation. Together, these factors lead to an exaggerated immune response against components of the gut microbiome.Genetic and Environmental InfluencesMultiple genetic...
35


