通过皮肤进行耳道迷走神经刺激可能会改善神经精神疾病中的认知缺陷 - - 一项系统性审查
Stefanie Theresa Jost1, Fabienne Happe1, Julian Koenig2
1Department of Neurology, University of Cologne, Faculty of Medicine and University Hospital Cologne, Cologne, Germany.
Frontiers in aging neuroscience
|February 20, 2026
概括
通过皮肤进行耳道迷走神经刺激 (taVNS) 可以改善神经精神疾病患者的认知功能. 这种非侵入性疗法对改善受影响个体的认知,注意力和记忆有前途.
科学领域:
- 神经科学是一个神经科学.
- 神经学 神经学
- 精神病学是一个精神病学.
背景情况:
- 通过皮肤进行耳道迷走神经刺激 (taVNS) 是治疗神经精神疾病的非侵入性疗法.
- 在这些条件下,认知障碍是一个重要的问题,影响功能结果.
- 在神经精神病患者群体中改善认知缺陷的taVNS的疗效尚未得到充分证实.
研究的目的:
- 系统地审查有关taVNS对神经精神疾病患者认知表现的影响的现有文献.
- 综合有关taVNS对各种认知领域的影响的发现.
主要方法:
- 在主要数据库 (PubMed,Embase,Cochrane) 进行了全面的文献搜索.
- 研究是根据预先定义的标准进行选择的,数据提取遵循PRISMA和SWiM指南.
- 使用Cochrane偏差风险和ROBINS-I工具评估方法质量.
主要成果:
- 在最终分析中包括了15项研究.
- 其中八项研究报告说,在taVNS之后,认知功能如全球认知,注意力,记忆,语言,执行功能或社会认知得到改善.
- 使用模式统计数据和因异质性而导致的范围来总结结果.
结论:
- taVNS显示了在患有神经精神疾病的个体中提高认知表现的潜力.
- 机制可能涉及脑干效应和神经网络调制.
- 为了证实这些发现,需要使用标准化方案进行进一步的研究,并进行更长的随访.
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