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肝细胞癌的立体性身体辐射疗法:综合性综述

Yupeng Di^1,2,3, Gang Ren⁴, Yingjie Wang³

¹Department of Radiation Protection Medicine, School of Preventive Medicine, Fourth Military Medical University, Xi'an, China.

Frontiers in oncology

|February 20, 2026

概括

立体性身体辐射疗法 (SBRT) 为肝细胞癌 (HCC) 提供了一个成熟的治疗方法. 这篇评论详细介绍了SBRT的细节.

科学领域:

辐射瘤学辐射瘤学
肝胆道恶性瘤肝胆道恶性瘤
医学物理医学物理

背景情况:

由于生物异质性和肝硬化,肝细胞癌 (HCC) 带来了挑战.
目前的管理需要多学科的方法来治愈的意图.

研究的目的:

审查立体性身体辐射疗法 (SBRT) 作为HCC的治疗意图模式.
在肝脏环境中分析SBRT的物理,放射生物学和剂量学方面.

主要方法:

审查SBRT原则,运动管理技术 (kV-PSI,MR指导) 和预后成像 (SULpeak,放射学).
在适应性放射治疗 (ART) 中评估SBRT与系统性药物 (TKIs,ICIs) 和AI的协同作用.

主要成果:

在其他癌症中,SBRT利用高剂量每小部分的成功.
先进的运动管理和成像提高SBRT精度用于肝脏瘤.
SBRT显示了与系统性药物的治疗协同作用,以及AI驱动的适应潜力.

结论:

SBRT是一种可行的,成熟的HCC治疗方法,可以适应肝脏微环境.
优化SBRT需要整合先进的技术,系统疗法和人工智能,以获得更好的结果.

关键词:

有效性有效性有效性.肝细胞癌是肝细胞癌.免疫疗法免疫疗法刻板印象性的身体辐射疗法.治疗的结果.

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