在移植患者中对疹杆菌的调查:单中心研究
Kei Sakurabayashi1, Masaki Muramatsu1, Yoshihiro Itabashi1
1Department of Nephrology, Faculty of Medicine, Toho University, Tokyo, Japan.
概括
疹 (shingles) 在移植后很常见,影响15.7%的患者. 风险因素包括功能下降和强烈的免疫抑制,即使在年轻人中也是如此.
科学领域:
- 腎臟病學 (nephrology) 是一種神經病學.
- 传染性疾病 传染性疾病
- 免疫学 免疫学 免疫学
背景情况:
- 疹 (shingles) 是移植后的一个严重并发症.
- 了解其发病率和风险因素对于患者管理至关重要.
研究的目的:
- 为了确定疹在成年脏移植接受者的发病率.
- 为了确定与疹发育和传播相关的独立风险因素.
主要方法:
- 从2013年4月到2023年3月,对714名成年移植接受者的回顾性评估.
- 计算每1000人/年发生率.
- 多变量后勤回归用于识别风险因素.
主要成果:
- 带状疹发生在15.7%的患者中,每1000人年发生率为22.1.
- 确定了独立的风险因素,包括估计的球过率降低和子抗淋巴细胞抗体的使用.
- 传播病例在使用抗淋巴细胞抗体时更为频繁.
结论:
- 疹是移植接受者的常见并发症,包括年轻人.
- 增加免疫抑制和功能受损与更高的风险和潜在传播有关.
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