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Updated: Feb 22, 2026

Author Spotlight: Innovative Use of nsPEF to Boost Peripheral Nerve Regeneration
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纳米粒子介导的免疫代谢-表观遗传重塑增强了施万细胞-巨细胞相互作用,用于坐骨神经再生

Wenying Xu1,2, Rongrong Wu1,2, Zhicheng Liu3

  • 1Shanghai Key Laboratory of Neuro-Ultrasound for Diagnosis and Treatment, Shanghai Sixth People's Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, China.

Advanced science (Weinheim, Baden-Wurttemberg, Germany)
|February 20, 2026
PubMed
概括

仿生普鲁士白色纳米粒子通过重编程巨细胞来促进坐骨神经的再生. 这种方法通过免疫代谢和表观遗传改造来增强神经修复,改善动物模型中的功能恢复.

关键词:
生物活性纳米材料免疫代谢的免疫代谢纳米医药是一种纳米医药.神经再生的神经再生坐骨神经受伤的伤害是什么?

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Neurogenesis and Regeneration of Nervous Tissue01:15

Neurogenesis and Regeneration of Nervous Tissue

In the CNS, neurogenesis, the birth of new neurons from stem cells, is limited to the hippocampus in adults. In other regions of the brain and spinal cord, neurogenesis is almost non-existent due to inhibitory influences from neuroglia, especially oligodendrocytes, and the absence of growth-stimulating cues. The myelin produced by oligodendrocytes in the CNS inhibits neuronal regeneration. Furthermore, astrocytes proliferate rapidly after neuronal damage, forming scar tissue that physically...
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