在韩国缺血性中风时风险因素控制状态的年度趋势
Joon-Tae Kim1, Ji Sung Lee2, Hyunsoo Kim1
1Department of Neurology, Chonnam National University Hospital Chonnam National University Medical School Gwangju Korea.
Journal of the American Heart Association
|February 20, 2026
概括
世俗趋势显示,在缺血性中风患者中,糖尿病,脂质失调和心房动 (AF) 的控制得到改善,但高血压控制下降. 尽管有所改善,但整体风险因素控制仍然不足以达到最佳水平,需要有针对性的干预措施.
科学领域:
- 心血管医学 心血管医学
- 神经学 神经学
- 公共卫生 公共卫生
背景情况:
- 评估在缺血性中风发作时主要风险因素控制的长期趋势.
- 评估现实世界对中风预防指南的遵守情况.
- 确定需要临床关注的领域,以改善早期中风的结果.
研究的目的:
- 在患有缺血性中风的患者中,评估控制主要风险因素 (高血压,糖尿病,失脂症,AF) 的长期趋势.
- 评估预防指南在临床实践中的实施情况.
- 确定需要针对性干预的领域,以获得更好的中风结果.
主要方法:
- 针对急性缺血性中风患者 (2011-2022) 的前性全国性注册表的回顾性分析.
- 确定的控制良好的风险因素:高血压 (静脉血压<140 mmHg),糖尿病 (HbA1c<7.0%),失脂症 (LDL-C<100 mg/dL) 和AF (服用口服抗凝剂).
- 使用Cochran-Armitage和线性对比测试来评估对照率的趋势.
主要成果:
- 调整后的良好控制的高血压率从35.7%降至25.5%.
- 得到良好控制的糖尿病,脂质不良和AF的发生率显著改善 (P<0.001).
- 脑卒中,心脏病发作和所有原因死亡的3个月复合结果从10.0%下降到8.6% (P<0.001).
结论:
- 糖尿病,失脂症和AF的前脑卒中风险因素控制增加了,但仍然不理想.
- 控制高血压的情况有所下降,这表明需要有针对性的战略.
- 调查结果突出了临床实践的优先领域和指导方针,以加强风险因素管理.
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